_A groundbreaking examination of a central question in international relations: Do states act rationally?_ To understand world politics, you need to understand how states think. Are states rational? Much of international relations theory assumes that they are. But many scholars believe that political leaders rarely act rationally. The issue is crucial for both the study and practice of international politics, for only if states are rational can scholars and policymakers understand and predict their behavior. John J. Mearsheimer and Sebastian (...) class='Hi'>Rosato argue that rational decisions in international politics rest on credible theories about how the world works and emerge from deliberative decision‑making processes. Using these criteria, they conclude that most states are rational most of the time, even if they are not always successful. Mearsheimer and Rosato make the case for their position, examining whether past and present world leaders, including George W. Bush and Vladimir Putin, have acted rationally in the context of momentous historical events, including both world wars, the Cold War, and the post–Cold War era. By examining this fundamental concept in a novel and comprehensive manner, Mearsheimer and Rosato show how leaders think, and how to make policy for dealing with other states. (shrink)

Le but de cet article, par l'introduction d'un terme spécifique, transocialisation, est de suggérer un fondement philosophique et théologique unifié pour des interprétations pratico-sociales, d'abord des actions de Jésus de Nazareth à table avec des pécheurs et à la Dernière Cène, puis de la transmutation et de la distribution des éléments du pain et du vin lors de la liturgie eucharistique, et, pour finir, de la grâce objective qui est immédiatement accordée aux communiants et de la grâce d'intention qui doit (...) se manifester dans leur pratique du don de soi. (shrink)

The author discusses the social influences that gave rise to the presumption in favor of children's participation in research and emphasizes the need for an ethical framework to guide decision-making in this context. Specifically, the author proposes a framework of child-centered bioethics that integrates the core bioethics principles of beneficence and autonomy with an assessment of children's needs and interests. Finally, the author articulates recommendations regarding mature minors and institutional review boards consistent with this framework in order to resolve the (...) difficult ethical issues posed by including children of all ages in clinical drug trials. (shrink)

In higher eukaryotes, circadian behaviour patterns have been dissected at the molecular level in Drosophila and, more recently, in the mouse. Considerable progress has been made in identifying some of the molecular components of the clock in the fly, where two genes, period (per) and timeless (tim), are essential for behavioural rhythmicity. The PER and TIM proteins show circadian cycles in abundance, and are part of a negative feedback loop with their own mRNAs. Within the pacemaker neurons, the PER and (...) TIM products are believed to form a complex which allows them to translocate to the nucleus, but how they repress their own transcription is unclear. TIM is rapidly degraded by light, a feature which permits a compelling molecular description of both behavioural light entrainment and phase responses to light pulses. The regulation of per and tim is altered in different Drosophila tissues, however, and comparative analyses of the two genes outside the Diptera reveals further unusual patterns of tissue‐specific regulation. Evolution appears to have modified the way in which the two genes are utilised to generate circadian phenotypes. More recently, the cloning of mouse clock genes, including putative per homologues, opens up exciting possibilities for mammalian molecular chronobiology. (shrink)

Much due criticism has been directed at Levinas's images of the feminine and “the Woman” in Time and the Other and Totality and Infinity, but less attention has been paid to the metaphor of maternity and the maternal body that Levinas employs in Otherwise Than Being. This metaphor should be of interest, however, because here we find an instance in which Levinas uses a female image without in any way seeming to exclude women from full ethical selfhood.In the first three (...) sections of this paper I explain how maternity functions in Otherwise Than Being. I argue that maternity is used as an image of the vulnerability or passive sensibility that characterizes the relation with the Other, as well as a metaphor for Levinas's account of ethical responsibility as substitution. In the final section of the paper, I defend the claim that Levinas's maternal metaphors are not disparaging to real, empirical women. I also discuss a remaining worry that feminists may have about the metaphor: namely, that it characterizes pregnancy and motherhood in ways that challenge some pro-choice assumptions. (shrink)

In higher eukaryotes, circadian behaviour patterns have been dissected at the molecular level in Drosophila and, more recently, in the mouse. Considerable progress has been made in identifying some of the molecular components of the clock in the fly, where two genes, period (per) and timeless (tim), are essential for behavioural rhythmicity. The PER and TIM proteins show circadian cycles in abundance, and are part of a negative feedback loop with their own mRNAs. Within the pacemaker neurons, the PER and (...) TIM products are believed to form a complex which allows them to translocate to the nucleus, but how they repress their own transcription is unclear. TIM is rapidly degraded by light, a feature which permits a compelling molecular description of both behavioural light entrainment and phase responses to light pulses. The regulation of per and tim is altered in different Drosophila tissues, however, and comparative analyses of the two genes outside the Diptera reveals further unusual patterns of tissue‐specific regulation. Evolution appears to have modified the way in which the two genes are utilised to generate circadian phenotypes. More recently, the cloning of mouse clock genes, including putative per homologues, opens up exciting possibilities for mammalian molecular chronobiology. (shrink)

Recent studies indicate that mammalian chromosomes contain discretecis‐acting loci that control replication timing, mitotic condensation, and stability of entire chromosomes. Disruption of the large non‐coding RNA gene ASAR6 results in late replication, an under‐condensed appearance during mitosis, and structural instability of human chromosome 6. Similarly, disruption of the mouse Xist gene in adult somatic cells results in a late replication and instability phenotype on the X chromosome. ASAR6 shares many characteristics with Xist, including random mono‐allelic expression and asynchronous replication timing. (...) Additional “chromosome engineering” studies indicate that certain chromosome rearrangements affecting many different chromosomes display this abnormal replication and instability phenotype. These observations suggest that all mammalian chromosomes contain “inactivation/stability centers” that control proper replication, condensation, and stability of individual chromosomes. Therefore, mammalian chromosomes contain four types ofcis‐acting elements, origins, telomeres, centromeres, and “inactivation/stability centers”, all functioning to ensure proper replication, condensation, segregation, and stability of individual chromosomes. (shrink)

Until a few years ago, the prevailing view was that children should not be participants in clinical research trials because children were incapable of consenting to such nontherapeutic interventions and are particularly vulnerable to abuse. That view has undergone a significant shift in the last few years, particularly in the context of trials to test the safety and effectiveness of drugs. A number of events facilitated this change, including the widespread off-label distribution of drugs to children and developments in the (...) AIDS epidemic. These social forces have shifted the core ethical question from whether children should be research subjects to when children should be research subjects.The presumption in favor of including children as research subjects for drug trials has manifested itself primarily through two different reforms: a 1997 federal statute and a set of regulations promulgated by the Food and Drug Administration that recently became effective. Together they reflect the view that children deserve the same access to safe and effective therapies as adults. (shrink)

Anselm’s Cur Deus homo [CDH hereafter] covers a number of topics related to the doctrine of redemption, but its main contribution to that doctrine is its account of how Christ’s death makes satisfaction for human sin. Anselm’s concept of satisfaction is correlated with his understanding of sin. According to Anselm, sin incurs a debt that one pays by making satisfaction. Anselm’s satisfaction theory of the Atonement came to dominate soteriology in the scholastic period. Despite numerous quotations from and references to (...) CDH among thirteenth- and fourteenth-century authors, we find that scholastics differ in how they interpret Anselm’s teaching on Christ’s satisfaction. This study will contribute to our .. (shrink)

In Le paradoxe de la morale, Vladimir Jankélévitch proposes that the moral life is a matter of balancing the demands of love, which call us to give without limit, and our natural, egoistical attachment to self, which he terms 'being'. This balancing act is ultimately paradoxical since love must both depend on and overcome being. The vision of moral life as a paradoxical balancing act of love and being, however, is implicitly challenged by another, "supernatural" vision of ethics that Jankélévitch (...) proposes near the end of the text. In these passages, the egoism of being that marks human nature is not merely balanced but genuinely transformed by the passionate care for an other. In this paper, these two visions of the ethical life offered by Jankélévitch's text are discussed in turn, and a way to read them as complementary rather than contradictory is proposed. (shrink)

At the start of Totality and Infinity, Emmanuel Levinas announces his project as one that will respond to the challenge of moral skepticism. Meanwhile, in a section titled “Skepticism and Reason” near the end of Otherwise than Being, Levinas interprets the recurrence of skepticism within philosophical reflection as a positive sign of the saying that refuses to be absorbed in the said. Here, I discuss the relationship between these two discussions of skepticism, and argue that Levinas’s appeal to a variety (...) of skepticism about language and reason is an important part of his answer to the moral skeptic. After first distinguishing between two challenges raised under the specter of moral skepticism at the start of Totality and Infinity, I demonstrate that Levinas answers both challenges, in part by appeal to the skepticism that he approves in “Skepticism and Reason.”. (shrink)

Almost from its origins, phenomenology has been modified in various ways by ‘phenomenologists’ who are inspired by Husserl but who deviate in significant ways from certain details of his approach. Jean-Paul Sartre and Emmanuel Levinas are two prime examples. While each is widely identified as a phenomenologist, each also departs from Husserl, the former by using phenomenology to pursue ontological questions and the latter by describing non-intentional modes of appearing. Here I argue that each is nevertheless rightly called a phenomenologist (...) for at least two reasons. First, each undertakes a careful study of the structure and contents of conscious experience in order to describe the foundations of the subject-object correlation and identify its conditions. Secondly, each accomplishes this by developing the notion of intentionality, focusing on the ways in which the intentional character of consciousness enables its lived encounter with what is transcendent to it. (shrink)

A historical investigation of the exclusion of Africa and Asia from modern histories of philosophy.

When Richard Rorty passed away in June of 2007, we lost a philosopher who contributed to a major number of philosophical currents, a thinker who, with his writing, managed to be at a height of an epoch. This interview was conducted during the year 2005–2006, and it has not been published in English. I publish it now as a way of honoring one of the most interesting philosophers of recent years.

When Richard Rorty passed away in June of 2007, we lost a philosopher who contributed to a major number of philosophical currents, a thinker who, with his writing, managed to be at a height of an epoch. This interview was conducted during the year 2005–2006, and it has not been published in English. I publish it now as a way of honoring one of the most interesting philosophers of recent years.

Vaesen infers unique properties of mind from the appearance of specific cultural innovation – a correlation without causal direction. Shifts in habitat, population density, and group dynamics are the only independently verifiable incentives for changes in cultural practices. The transition from Acheulean to Late Stone Age technologies requires that we consider how population and social dynamics affect cultural innovation and mental function.

The first English translation of Fichte’s second set of 1804 lectures on the Wissenschaftslehre.

Orthologic is defined by weakening the axioms and rules of inference of the classical propositional calculus. The resulting Lindenbaum-Tarski quotient algebra is an orthoimplication algebra which generalizes the author's implication algebra. The associated order structure is a semi-orthomodular lattice. The theory of orthomodular lattices is obtained by adjoining a falsity symbol to the underlying orthologic or a least element to the orthoimplication algebra.

Providing an original and systematic treatment of foundational issues in philosophy of religion, J. L. Schellenberg's new book addresses the structure of..

According to realist structuralism, mathematical objects are places in abstract structures. We argue that in spite of its many attractions, realist structuralism must be rejected. For, first, mathematical structures typically contain intra-structurally indiscernible places. Second, any account of place-identity available to the realist structuralist entails that intra-structurally indiscernible places are identical. Since for her mathematical singular terms denote places in structures, she would have to say, for example, that 1 = − 1 in the group (Z, +). We call this (...) the identity problem and conclude that nominalism is presently the safest route for the structuralist. (shrink)

Ned Block argues that the higher-order (HO) approach to explaining consciousness is ‘defunct’ because a prominent objection (the ‘misrepresentation objection’) exposes the view as ‘incoherent’. What’s more, a response to this objection that I’ve offered elsewhere (Weisberg 2010) fails because it ‘amounts to abusing the notion of what-it’s-like-ness’ (xxx).1 In this response, I wish to plead guilty as charged. Indeed, I will continue herein to abuse Block’s notion of what-it’s-like-ness. After doing so, I will argue that the HO approach accounts (...) for the sense of what-it’s-like-ness that matters in a theory of consciousness. I will also argue that the only incoherence present in the HO theory is that generated by embracing Block’s controversial notion of what-it’s-like-ness, something no theorist of any stripe ought to do. Block is famous for (among other things) having introduced the notion of ‘phenomenal consciousness’ into contemporary philosophy of mind (Block 1995). This term is widely employed in the philosophical literature and it even appears in the empirical literature. But wide-speared usage has brought about divergent interpretations of the term. We can distinguish a ‘moderate’ and a ‘zealous’ reading of ‘phenomenal consciousness’. On the moderate reading, ‘phenomenal consciousness’ just means ‘experience’. Many people have embraced this sense of the term and use it to roughly pick out conscious experience involving sensory quality (states like conscious visual experiences or conscious pains, for example).2 On the zealous reading, however, phenomenal consciousness is held to be ‘distinct from any cognitive, intentional, or functional property’ (Block 1995: 234). That is, any explanation of phenomenal consciousness in exclusively cognitive, intentional, or functional terms will fail to capture, without remainder, what is really distinctive about phenomenal consciousness. Block, of course, is fully clear about embracing the zealous reading; indeed, his initial introduction of the notion is in those terms. The same ambiguity occurs with the much-used (and abused) idea of ‘what-it’s-like-ness’.. (shrink)

Scientists and laypeople alike use the sense of understanding that an explanation conveys as a cue to good or correct explanation. Although the occurrence of this sense or feeling of understanding is neither necessary nor sufficient for good explanation, it does drive judgments of the plausibility and, ultimately, the acceptability, of an explanation. This paper presents evidence that the sense of understanding is in part the routine consequence of two well-documented biases in cognitive psychology: overconfidence and hindsight. In light of (...) the prevalence of counterfeit understanding in the history of science, I argue that many forms of cognitive achievement do not involve a sense of understanding, and that only the truth or accuracy of an explanation make the sense of understanding a valid cue to genuine understanding. (shrink)

The purpose of this text is to draw attention to eight forgotten heroes: William C. Bagley, Charles DeGarmo, David Felmley, William Torrey Harris, Isaac L. Kandel, Charles McMurry, William C. Ruediger, and Edward Austin Sheldon. They have been marginalized from our profession, and drawing upon their legacy is the best hope for restoring the profession of teaching today. This work also includes a chapter at the end of the book entitled "John Dewey's Forgotten Essays." The audience for this book includes: (...) 1) classroom teachers, 2) school administrators, 3) teacher educators, 4) deans and other university administrators, 5) college and university presidents, 6) legislators, 7) historians of education, 8) curriculum specialists, 9) specialists in teacher training, and 10) the general public. (shrink)